Hepatitis C Virus is a single-stranded, positive RNA flavivirus that causes severe liver disease. Initial and early chronic infection is usually mild or asymptomatic, but often progresses to liver disease, cirrhosis, liver failure and liver cancer. Transmission is primarily by blood-to-blood contact associated with intravenous drug use or transfusions, affecting an estimated 170 million people annually.
The HCV core protein is a structural protein that forms an icosahedral protective shell surrounding the viral RNA. The mature viral particle is further encased in a lipid (fatty) envelope of cellular origin into which viral glycoproteins E1 and E2 are embedded. It is highly immunogenic and as such a good candidate for HCV detection.
Caution: This product is intended for research or manufacturing use only.
|Appearance||clear colorless liquid|
|Mol Weight||approx 16.8kDa|
|Buffer||Phosphate Buffered Saline pH7.4|
|Activity||Binds HCV positive serum antibodies|
|Shipping||Shipped on blue ice|
|Storage||4 C, or aliquot and store at -20C|
|Expression System||E. Coli|
|Assay Method(s)||SDS-PAGE (purity),
Immunoblot (reactivity sera)
|Application||Suitable for use in ELISA, Western Blot
& lateral flow assays. Each laboratory
should determine optimum working titre
for use in it’s particular application
|Expiry Date||As indicated|
|Production Date||As indicated|
|Assay Date||As indicated|
|Lot #||As indicated|