HCV NS3

Hepatitis C Virus is a single-stranded, positive RNA flavivirus that causes severe liver disease. Initial and early chronic infection is usually mild or asymptomatic, but often progresses to liver disease, cirrhosis, liver failure and liver cancer. Transmission is primarily by blood-to-blood contact associated with intravenous drug use or transfusions, affecting an estimated 170 million people annually.

Nonstructural protein 3 (NS3), is a nonstructural viral protein derived from the HCV polyprotein. It is an essential viral protein with serine protease and RNA helicase activity. It is expressed early in the viral replication cycle and as such is a good candidate for early detection of infection.

Caution: This product is intended for research or manufacturing use only.

Product Details:

Product # BA12-C
Size 1mg
Appearance solid white powder
Purity >95%
Mol Weight approx 48.7kDa
Concentration 1.0 mg/ml when reconstituted as recommended
Buffer 20mM Carbonate pH9.6
Activity Binds HCV positive serum antibodies
Shipping Shipped at ambient temperature
Storage 15-25 C lyophilized;
4 C when reconstituted
Expression System E. Coli
Assay Method(s) SDS-PAGE (purity),
Immunoblot (reactivity sera)
Application Suitable for use in ELISA, Western Blot
& lateral flow assays. Each laboratory
should determine optimum working titre
for use in it’s particular application
Expiry Date As indicated
Production Date As indicated
Assay Date As indicated
Lot # As indicated