The strains of HIV-1 can be classified into four groups. The most important group, M, is the ‘major’ group and is responsible for the majority of HIV infections worldwide. The other three groups are N, O and P. They are quite uncommon and occur predominantly in Cameroon, Gabon and Equatorial Guinea. The most prevalent of these subtypes is Group O which accounts for 2% of HIV infections in Cameroon. By comparison, Group N accounts for only 0.1% while Group P is extremely rare and accounts for only 0.06% of HIV infections in Cameroon.
HIV-1 Group M gp41 does not cross react with Group O positive serum, and therefore inclusion of Group O variant of gp41 is important for the positive identification of HIV-1 Group O variant positive patients.
Caution: This product is intended for research or manufacturing use only.
|Appearance||solid white powder|
|Mol Weight||approx 13.0kDa|
|Concentration||1.0 mg/ml when reconstituted as recommended|
|Buffer||20mM Na-carbonate, pH9.6|
|Activity||Binds HIV-1 positive serum antibodies|
|Shipping||Shipped at ambient temperature|
|Storage||15-25 C lyophilized;
4 C when reconstituted
|Expression System||E. Coli|
|Assay Method(s)||SDS-PAGE (purity),
Immunoblot (reactivity sera)
|Application||Suitable for use in ELISA, Western Blot
& lateral flow assays. Each laboratory
should determine optimum working titre
for use in it’s particular application
|Expiry Date||As indicated|
|Production Date||As indicated|
|Assay Date||As indicated|
|Lot #||As indicated|