Syphilis TpN47

The causative agent of Syphilis is a bacterium: Treponema pallidum. The immune responses to T. pallidum are primarily mediated by the following membrane lipoproteins: TpN47, TpN17, TpN15 and TmpA. TpN47 is highly immunogenic and activates endothelial cells, while TpN17 and TpN15 induce antibody responses.

In independent studies, TmpA is the most frequently identified antigen (95%) while the remaining are recognised with the following prevalence: TpN47, 92.5%; TpN17, 89.5%; and TpN15, 67.5%.

Product Details:

Product # BA09-C
Size 0.8 mg
Appearance solid white powder
Purity >95%
Mol Weight approx 47.7 kDa
Concentration 0.8 mg/mL when reconstituted as recommended
Buffer

20mM Carbonate pH10.0

Activity Binds Syphilis antibodies
Shipping Shipped at ambient temperature
Storage 15-25 C lyophilized;
4 C when reconstituted
Expression System E. Coli
Assay Method(s) SDS-PAGE (purity)
Application Suitable for use in ELISA, Western Blot
& lateral flow assays. Each laboratory
should determine optimum working titre
for use in it’s particular application
Expiry Date As indicated
Production Date As indicated
Assay Date As indicated
Lot # As indicated